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Scientific Publications – Test 01
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Case Studies & Program Insights – Test 01
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MedPharm’s Center for Skin Biology: The Standard of Quality
MedPharm’s Center for Skin Biology (CSB) provides scientifically rigorous, end-to-end support for substantiating cosmetic and personal care claims. With over 25 years of skin biology expertise, proprietary human skin models, and integrated preclinical and clinical capabilities, CSB generates reliable, performance-based data to support product claims and differentiate brands in a competitive market.
Reducing API Concentration While Preserving Topical Drug Performance
This case study shows how MedPharm reduced API concentration in a topical formulation while maintaining drug performance. By optimizing excipient composition and improving thermodynamic activity, the team achieved equivalent skin permeation, reduced cost of goods, and supported successful clinical development and commercialization.
Blog: Unlocking the Potential of Nasal Drug Delivery: Strategies for Formulation Success
Technical Blog
Published: November 2025
Authors: Dr. Jon Lenn, Dr. Charles Evans, and Dr. Jon Volmer
Advancing Nasal Drug Delivery Through Formulation Strategy
Nasal drug delivery is an increasingly important route of administration for local and systemic therapies, including treatments for allergic rhinitis, migraines, vaccines, and central nervous system disorders. Compared with oral and injectable dosage forms, nasal delivery can offer rapid absorption, non-invasive administration, and improved patient adherence. However, the nasal cavity presents significant biological barriers that can limit drug residence time and absorption.
In this technical blog, MedPharm explores practical strategies for overcoming nasal delivery challenges, including formulation design considerations, device compatibility, and the use of advanced preclinical models to support successful development.
What’s Covered in This Technical Blog
- Why nasal drug delivery continues to gain momentum across multiple therapy areas
- Key anatomical and physiological barriers that impact nasal absorption
- Strategic considerations for solution versus suspension-based formulations
- The role of formulation characterization in improving residence time and performance
- How advanced nasal models can help de-risk development and accelerate timelines
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Complete the form to read the full blog and learn how MedPharm helps developers unlock the full potential of nasal drug delivery through proven formulation strategies and innovative preclinical tools.
Article: Alternative Drug Delivery Routes: Opportunities, Challenges, and How to Overcome Them
Nasal Drug Delivery: Opportunities, Challenges, and Formulation Strategies
Technical Article
Published: September 2025
Authors: Dr. Jon Lenn, Dr. Charles Evans, Dr. Jon Volmer
Advancing Alternative Drug Delivery Through Scientific Expertise
Nasal drug delivery is an increasingly important route of administration for local, systemic, and central nervous system therapies. Compared with oral and injectable dosage forms, nasal formulations can enable rapid onset of action, reduce systemic exposure, and improve patient adherence. However, biological barriers, rapid clearance mechanisms, and device-dependent delivery introduce formulation challenges that require specialized expertise.
In this technical article, MedPharm examines key considerations for nasal drug delivery within the broader context of alternative topical and transepithelial routes of administration. The article highlights route-specific challenges, formulation and device strategies, and the role of preclinical models in de-risking development and accelerating timelines.
What’s Covered in This Technical Article
- Core principles of nasal drug delivery and biological barriers
- Common formulation challenges and development considerations
- Strategies to optimize residence time, absorption, and targeting
- The impact of formulation–device interactions on delivery performance
- How preclinical nasal models support formulation selection and reduce risk
📥 Download the Technical Article
Complete the form to access the full technical article and explore MedPharm’s approach to nasal drug delivery and alternative routes of administration.
Nasal Technical Article
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File Download – Nasal Technical Article
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