Quantitative Bioanalysis Across In Vitro and In Vivo Systems
MedPharm delivers bioanalytical services to support quantitative bioanalysis across in vitro and in vivo systems.
A key drug development challenge is understanding how a compound moves across different systems, including in vitro models and biological matrices. Bioanalytical studies quantify drug levels across a wide range of sample types.
MedPharm supports programs from in vitro release and permeation testing through in vivo biological sample analysis, generating reliable data to guide development decisions.
Regulatory-Grade Skin, Mucosal, and Transdermal Permeation Studies
What is In Vitro Permeation and Penetration Testing (IVPT)?
The in vitro permeation and penetration test (IVPT) is a well-validated method for studying percutaneous absorption and determining the pharmacokinetics of topically applied drugs. Because in vivo testing is often costly, time-consuming, and difficult to conduct, most topical and transdermal developers rely on in vitro and ex vivo IVPT methodologies to optimize and compare formulations.
Science-Led Formulation Development for Topical and Transdermal Products
Overview
MedPharm delivers topical and transdermal formulation development to support pharmaceutical programs from early-stage research through clinical and commercial outcomes. Our science-led approach integrates pre-formulation, formulation development, device considerations, and IP strategy to reduce risk, control timelines, and enable successful product development.
Analytical Services
MedPharm delivers topical and transdermal analytical services to support pharmaceutical development from early-stage research through commercial release.
Developing analytical methods for a New Chemical Entity (NCE) can be challenging when limited information is available. MedPharm addresses these gaps early through integrated analytical and formulation expertise.
Our scientists design analytical methods aligned to the stage and objectives of each program, then refine and validate those methods to support progression through development and into commercial release.
MedPharm also brings extensive experience in analytical development for generic drug products, enabling the rapid development of reliable, regulatory-ready methods.
