This case study highlights how MedPharm expanded formulation space to strengthen intellectual property and increase commercial value for a topical drug product. By developing and evaluating multiple formulation types, including gels, creams, ointments, and foams, MedPharm enabled broader patent coverage while maintaining consistent product performance. The result was a more defensible IP strategy, reduced competitive […]

This case study shows how MedPharm reduced API concentration in a topical formulation while maintaining drug performance. By optimizing excipient composition and improving thermodynamic activity, the team achieved equivalent skin permeation, reduced cost of goods, and supported successful clinical development and commercialization. Download Case Study

This case study shows how MedPharm, in collaboration with GSK and the University of Reading, demonstrated the skin penetration and biological activity of a large aptamer using advanced skin models. The findings challenge traditional molecular weight limits in topical drug delivery and highlight the potential for large-molecule therapies in dermatology. Download Case Study

This case study shows how MedPharm worked with Reckitt scientists to develop clinically relevant pharynx models for comparing drug delivery from a throat spray and a lozenge formulation. Using ex vivo and human tissue models, the team demonstrated equivalent flurbiprofen permeation across both dosage forms and supported the determination of a clinically relevant dose. These […]

This case study shows how MedPharm used process development to support clinical trial supply for a complex topical formulation. By identifying critical process parameters and optimizing manufacturing conditions, the team improved product consistency and reduced scale-up risk. The optimized process enabled reliable, reproducible production of clinical batches and ensured on-time delivery for a Phase 2 […]