This blog explores the challenges and opportunities of nasal drug delivery, including formulation strategies, biological barriers, and targeting approaches for local and systemic therapies. It also highlights MedPharm’s expertise in preformulation, characterization, and advanced nasal models designed to support successful product development

The global cosmetics market is growing rapidly, driven by consumer demand, social media influence, and interest in science-backed, personalized skincare. As scrutiny of product claims increases, advanced testing is becoming essential. This article highlights the evolving landscape of cosmetic testing and how MedPharm’s Center for Skin Biology supports robust, evidence-based claims.

This case study shows how MedPharm demonstrated the clinical efficacy and tolerability of MedSpray® in a non-inferiority study against a marketed antifungal treatment. Building on strong preclinical performance, the optimized MedSpray® formulation delivered equivalent antifungal activity while improving tolerability and maintaining comparable recurrence rates. These results confirm that enhanced topical drug delivery can translate into […]

This case study shows how MedPharm improved topical and transdermal drug delivery performance using MedSpray® film-forming technology. By optimizing formulation design and comparing performance against marketed patches, gels, and creams, MedSpray® demonstrated higher drug permeation, improved release profiles, and greater formulation flexibility. Download Case Study

This case study shows how MedPharm improved topical and transdermal drug delivery using its MedSpray® film-forming technology. By combining thermodynamically optimized formulations with an aerosol-based delivery system, MedSpray® enhanced drug permeation through the skin, increased tissue retention, and enabled both immediate and sustained release profiles. The result was improved formulation performance, better patient usability, and […]

This case study shows how MedPharm improved IVPT performance using MedFlux-HT®, an automated flow-through diffusion system. By maintaining optimal sink conditions and increasing sensitivity, MedFlux-HT® generated more reliable permeation data and enabled better formulation decisions. Download Case Study

This case study shows how MedPharm optimized skin explant models to improve stability and extend tissue viability for inflammation and wound healing studies. By preserving physiological relevance and enabling multi-endpoint analysis, the model generated more predictive data and supported better development decisions. Download Case Study

This case study shows how MedPharm developed a reconstructed nasal epithelium (RNE) model to improve prediction of nasal drug delivery performance. By replicating key physiological features and benchmarking against clinical data, the model generated more reliable, human-relevant data and supported better formulation decisions. Download Case Study

This case study shows how MedPharm improved nasal drug delivery modeling using advanced in vitro systems, including reconstructed human nasal epithelium and CT-based nasal casts (MedCast®). These approaches generated more predictive data, improved in vitro to in vivo correlation, and supported better formulation and development decisions. Download Case Study

This case study shows how MedPharm resolved scale-up stability challenges by identifying process-driven root causes and optimizing manufacturing parameters. Through targeted studies and process optimization, variability was reduced and a robust, reproducible scale-up strategy was established. Download Case Study