Ungual Delivery
Optimized Formulations for Nail and Hard Tissue Penetration
At MedPharm, we specialize in ungual drug delivery, focusing on the development of advanced topical formulations designed to penetrate the hard keratin structure of nails. Our solutions are effective for treating onychomycosis, nail psoriasis, and various other nail-related conditions. Our scientifically-driven formulation strategies, penetration enhancement technologies, and in-vitro testing expertise ensure that ungual drug products achieve optimal bioavailability, sustained retention, and enhanced therapeutic efficacy.
With customized excipients, controlled-release mechanisms, and permeability optimization, MedPharm’s ungual drug delivery solutions provide targeted treatment, leading to improved patient compliance and success in meeting regulatory requirements.
Our Expertise in Ungual Drug Delivery
Optimized Formulations for Nail Penetration
- Lacquers, gels, and solutions for enhanced drug absorption
- Mucoadhesive formulations for prolonged retention
- Polymer-based delivery systems for controlled release
- pH-balanced and non-irritating excipient selection
Advanced Penetration Enhancement Technologies
- Customized excipients to improve keratin permeability
- Nanoparticle and lipid-based delivery systems
- Chemical penetration enhancers for increased drug diffusion
- In-vitro permeation testing to evaluate nail penetration efficacy
In Vitro Testing and Bioavailability Optimization
- Specialized nail penetration models for bioequivalence testing
- Permeability assessment using in vitro permeation testing (IVPT) techniques
- Controlled-release profiling for long-term therapeutic action
- Regulatory-compliant analytical and stability studies
GMP-Compliant Manufacturing and Regulatory Support
- Comprehensive formulation support from development to commercialization
- Batch-to-batch consistency with stringent quality control
- ICH-compliant stability and release testing for ungual products
- Regulatory assistance for Investigational New Drug (IND), New Drug Application (NDA), Abbreviated New Drug Application (ANDA), and global market approvals
Advantages of MedPharm’s Ungual Drug Delivery Solutions
- Targeted drug delivery with optimized penetration through the nail plate
- Customizable formulation approaches for sustained-release treatments
- Regulatory-compliant in vitro testing to support IND, NDA, and ANDA submissions
- GMP-compliant manufacturing for both clinical and commercial supply
- Seamless integration from early-stage development to full-scale production
Why Choose MedPharm for Ungual Drug Delivery?
- Industry-leading expertise in nail penetration and hard tissue drug formulations
- Advanced permeation technologies for improved bioavailability
- Regulatory-compliant analytical testing and stability studies
- Seamless scale-up for clinical and commercial manufacturing
- Specialized in vitro testing for nail permeation and bioequivalence
Develop Market-Ready Ungual Drug Products with MedPharm
With specialized expertise in ungual drug delivery, MedPharm ensures your nail and hard tissue formulations are developed with precision, efficacy, and regulatory compliance, helping you achieve clinical and commercial success.
