Our Gastrointestinal Delivery Capabilities Include:

Mucosal Absorption Strategies

• Buccal, esophageal, rectal, and intestinal formulations for local and systemic action
• Expertise in permeation enhancers and bioadhesive technologies
• Development of gels, suppositories, and liquid formulations optimized for retention and absorption

Stability and Release Optimization

• Protection of sensitive APIs from enzymatic or acidic degradation
• Targeted-release profiles to ensure drug delivery at the optimal site within the GI tract
• Formulation technologies such as mucoadhesive systems and enteric coatings

Disease-Specific Focus

• Formulations for inflammatory conditions (e.g., Crohn’s disease, ulcerative colitis)
• Treatments for infections, motility disorders, and local GI cancers
• GI mucosal barrier repair and regenerative medicine approaches

Customized Testing Models

• In vitro and ex vivo models replicating human GI tissue environments
• Permeation and irritation testing under simulated GI conditions
• Bioavailability and pharmacokinetic assessments tailored to GI drug delivery

Why Choose MedPharm for Gastrointestinal Drug Development?

• Deep expertise in overcoming GI-specific formulation challenges
• Proven experience with mucosal absorption and site-specific targeting
• Integrated development services from pre-formulation through clinical supply
• Regulatory support for IND, NDA, and global market submissions