Targeted and Sustained Drug Delivery for Complex Anatomical Sites

Overview

MedPharm supports the development and testing of formulations for unconventional and complex routes of administration, including:

• Intravesical (bladder)
• Intra-articular (joint)
• Otic (ear)

These delivery routes enable localized, targeted, and sustained or controlled drug release to specific organs and cavities.

Topical and Transdermal Drug Delivery Through Human Skin

MedPharm’s Formulation Strategy

MedPharm’s formulation strategy is applied consistently across all routes of delivery, where excipients and formulation design are selected based on the drug and the target product profile to optimize stability and delivery to the site of action.

The site of action may be:

• Local (skin, nail, nose, eye, and other topical routes), or
• Systemic (transdermal or transepithelial)

Formulation ingredients are selected to address the unique barrier properties of each epithelial tissue. For certain routes, the delivery device is also critical and must be considered early in development.

When developing a medicine, the patient is not given a drug, but a drug product. Every component of the formulation and device contributes to delivering the drug to its intended target.

Nasal and Pulmonary Formulation Development and Delivery Models

MedPharm’s Formulation Strategy

MedPharm’s formulation strategy is applied across all epithelial routes of delivery, where excipients and formulation design are selected based on the drug and the target product profile to optimize stability and delivery to the site of action.

The site of action may be:

• Local (skin, nasal, eye, etc.), or
• Systemic (transdermal or transepithelial)

Formulation ingredients are selected to address the unique barrier properties of each epithelial tissue.

Ungual Drug Delivery, Nail IVPT, and Onychomycosis Models

MedPharm’s Formulation Strategy

MedPharm’s formulation strategy is applied across all epithelial routes of delivery, where excipients and formulation design are selected based on the drug and the target product profile to optimize stability and delivery to the site of action.

The site of action may be:

• Local (skin, nasal, eye, etc.), or
• Systemic (transdermal or transepithelial)

Formulation ingredients are selected to address the unique barrier properties of each epithelium.

Ophthalmic Formulation Development and Ocular Drug Delivery Models

MedPharm’s Formulation Strategy

MedPharm’s formulation strategy is applied across all epithelial routes of delivery, where excipients and formulation design are selected based on the drug and the target product profile to optimize stability and delivery to the site of action.

The site of action may be:

• Local (skin, nasal, eye, etc.), or
• Systemic (transdermal or transepithelial)

Formulation ingredients are chosen to address the unique barrier properties of each epithelium.